Back to Search Start Over

FACILE REGIOSELECTIVE MONOBROMINATION OF ANILINES AND PHENOLS THROUGH GREEN PROTOCOL AND EVALUATION OF THEIR BIOACTIVITY.

Authors :
Sarma, Madhushree Das
Ghosh, Subhojit
Source :
Rasayan Journal of Chemistry. Jan2021, Vol. 14 Issue 1, p19-28. 10p.
Publication Year :
2021

Abstract

Several bromoanilines and bromophenols were synthesized in good to nearly quantitative yields using a mixture of potassium bromide and potassium bromate in presence of dilute acid under mild conditions in a short time. Some of the prepared Bromo derivatives showed fairly strong antioxidant properties when screened for in vitro antioxidant activity using 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical and compared with standard natural antioxidant Lascorbic acid. Most of the synthesized Bromo compounds displayed broad-spectrum activity against Bacillus subtilis, but except one, they were found to be inactive against Escherichia coli. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
09741496
Volume :
14
Issue :
1
Database :
Academic Search Index
Journal :
Rasayan Journal of Chemistry
Publication Type :
Academic Journal
Accession number :
148269923
Full Text :
https://doi.org/10.31788/rjc.2021.1416098