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Existují rozdíly v tloušťce a ploše neokortexu mezi pacienty po první epizodě schizofrenie a zdravými kontrolami?
- Source :
-
Czech Radiology / Ceska Radiologie . pro2020, Vol. 74 Issue 4, p268-274. 7p. - Publication Year :
- 2020
-
Abstract
- Purpose: To asses cerebral cortical thickness and area changes in the earliest stage of schizophrenia. Methods: Magnetic resonance was used to prospectively compare cerebral cortex thickness and surface area between subjects after the first episode of schizophrenia (n = 15) and healthy controls (n = 19). The subjects were examined on a 3 Tesla MRI system equipped with a 64-channel head coil. Surface-based morphometry was performed on 3D T1- and T2-weighted data by using Freesurfer software package (ver. 7.1.0). Results: No statistically significantly different clusters of cerebral cortical surface / thickness were found between both groups of subjects. Conclusion: Contrary to the observations published by other authors including large multicentric studies, no statistically significant differences in cerebral cortical thickness or area were found in the earliest stage of schizophrenia. [ABSTRACT FROM AUTHOR]
Details
- Language :
- Czech
- ISSN :
- 12107883
- Volume :
- 74
- Issue :
- 4
- Database :
- Academic Search Index
- Journal :
- Czech Radiology / Ceska Radiologie
- Publication Type :
- Academic Journal
- Accession number :
- 148329093