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Asymptomatic Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection in a Rehabilitation Facility: Evolution of the Presence of Nasopharyngeal SARS-CoV-2 and Serological Antibody Responses.
- Source :
-
Journal of Infectious Diseases . 1/15/2021, Vol. 223 Issue 2, p192-196. 5p. - Publication Year :
- 2021
-
Abstract
- At the start of the UK coronavirus disease 2019 epidemic, this rare point prevalence study revealed that one-third of patients (15 of 45) in a London inpatient rehabilitation unit were found to be infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) but asymptomatic. We report on 8 patients in detail, including their clinical stability, the evolution of their nasopharyngeal viral reverse-transcription polymerase chain reaction (RT-PCR) burden, and their antibody levels over time, revealing the infection dynamics by RT-PCR and serology during the acute phase. Notably, a novel serological test for antibodies against the receptor binding domain of SARS-CoV-2 showed that 100% of our asymptomatic cohort remained seropositive 3-6 weeks after diagnosis. [ABSTRACT FROM AUTHOR]
- Subjects :
- *COVID-19
*SARS-CoV-2
*ANTIBODY formation
*POLYMERASE chain reaction
Subjects
Details
- Language :
- English
- ISSN :
- 00221899
- Volume :
- 223
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- Journal of Infectious Diseases
- Publication Type :
- Academic Journal
- Accession number :
- 148482010
- Full Text :
- https://doi.org/10.1093/infdis/jiaa610