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Peripheral edema in an individual with treatment resistant major depressive disorder treated with olanzapine/fluoxetine combination.
- Source :
-
University of Toronto Medical Journal . 2021, Vol. 98 Issue 1, p100-102. 3p. - Publication Year :
- 2021
-
Abstract
- Olanzapine/fluoxetine combination therapy is a widely prescribed antipsychotic-antidepressant regimen for treatment resistant depression and is reported to have a side effect of peripheral edema. The theoretical underpinnings of peripheral edema in association with olanzapine/fluoxetine combination therapy are still unclear. Although peripheral edema associated with olanzapine/fluoxetine combination is rarely reported, the mechanism of drug interaction and effect on cytochrome P450 enzymes may induce it. We review the case of a middle-aged patient, who presented with peripheral edema after the administration of olanzapine/fluoxetine combination therapy. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 08332207
- Volume :
- 98
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- University of Toronto Medical Journal
- Publication Type :
- Academic Journal
- Accession number :
- 148506676