Intramatricial low‑dose secukinumab injection for nail psoriasis.

This preliminary pilot therapy showed that low-dose secukinumab intramatricial injection seems to be a quick, effective and safe treatment method for nail psoriasis. The severity of each nail was evaluated using the target nail psoriasis severity index scores, which allows a probable target nail score of 0 to 32. 3 The baseline scores were 12, 10 and 8 for case 1 [Figure 1a], and 14, 12 and 12 for case 2 [Figure 2a]. © 2021 Indian Journal of Dermatology, Venereology and Leprology- Published by Scientific Scholar 116 Intramatricial low-dose secukinumab injection for nail psoriasis Sir, Nail psoriasis affects not only the nail structure and function; it can also adversely impact the psychological state in psoriasis patients. [Extracted from the article]