Secondary metabolites from a deep-sea-derived Aspergillus versicolor F77.

Chemical examination of fermentation products of a deep-sea-derived fungus Aspergillus versicolor F77 led to the isolation of two new compounds acetyl-sydonol (1) and 2-hydroxydiorcinol D (2), a new natural product 1-(2,4-dimethoxyphenyl)-1,2-dihydro-3H-pyrazol-3-one (3), together with four known compounds sydonol (4), (S)-sydonic acid (5), aspergillusene A (6) and diorcinol D (7). Their structures were determined through the extensive spectroscopic analysis and comparison with the reported data in literature. Compound 6 showed moderate NF-κB inhibitory activity. [ABSTRACT FROM AUTHOR]