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Silver‐Catalyzed [3+1+1] Annulation of Nitrones with Isocyanoacetates as an Approach to 1,4,5‐Trisubstituted Imidazoles.
- Source :
-
European Journal of Organic Chemistry . 2/12/2021, Vol. 2021 Issue 6, p964-968. 5p. - Publication Year :
- 2021
-
Abstract
- A silver‐catalyzed protocol for [3+1+1] annulation of nitrones and isocyanoacetates is reported. The reaction is proposed to proceed through sequential [3+2] cycloaddition, ring‐opening, cyclization‐oxidation, and dealkylation, allowing access to a broad scope of valuable polysubstituted imidazoles in high yields. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 1434193X
- Volume :
- 2021
- Issue :
- 6
- Database :
- Academic Search Index
- Journal :
- European Journal of Organic Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 148723437
- Full Text :
- https://doi.org/10.1002/ejoc.202001536