Back to Search
Start Over
Adenosquamous carcinoma of the breast, an uncommon diagnosis with poor prognosis—Lessons learned from a 12‐year analysis of the National Cancer Database.
- Source :
-
Breast Journal . Feb2021, Vol. 27 Issue 2, p165-169. 5p. - Publication Year :
- 2021
-
Abstract
- We compared the clinicopathologic characteristics and prognosis of adenosquamous carcinoma (ASQ) of the breast with invasive ductal carcinoma (IDC), utilizing the National Cancer Database (NCDB) from 2004 to 2015. 1 932 688 female patients had invasive breast carcinoma; 1 421 250 had IDC (73.5%); and 453 had ASQ (0.0002%). When compared to IDC, ASQ patients were significantly (P <.05) older and had grade 1 tumors; negative lymph nodes; ER/PR/HER2‐negative tumors; and worse 5‐year overall survival (64.9% vs 74%, respectively). Our study, largest to date on ASQ, revealed an aggressive carcinoma with a significantly worse prognosis than IDC. "Personalized medicine" treatment approach for patients with this uncommon carcinoma is needed. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 1075122X
- Volume :
- 27
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- Breast Journal
- Publication Type :
- Academic Journal
- Accession number :
- 148724201
- Full Text :
- https://doi.org/10.1111/tbj.14135