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Therapeutic advances of miRNAs: A preclinical and clinical update.
- Source :
-
Journal of Advanced Research . Feb2021, Vol. 28, p127-138. 12p. - Publication Year :
- 2021
-
Abstract
- miRNAs, a class of small endogenous RNAs, are one of the essential biopharmaceuticals which are in commercial spans as next-generation medicine in recent times. A snapshot of the current scenario regarding the miRNAs as biopharmaceuticals have been discussed. In this work, biopharmaceutical companies working with miRNAs and the current status of preclinical/clinical trials about miRNA therapeutics have been reviewed. Finally, recent updates on the absorption, distribution, metabolism, and excretion (ADME), as well as a delivery system of miRNAs, have been illustrated. [ABSTRACT FROM AUTHOR]
- Subjects :
- *MICRORNA
*NON-coding RNA
*BIOPHARMACEUTICS
*CLINICAL trials
Subjects
Details
- Language :
- English
- ISSN :
- 20901232
- Volume :
- 28
- Database :
- Academic Search Index
- Journal :
- Journal of Advanced Research
- Publication Type :
- Academic Journal
- Accession number :
- 148729975
- Full Text :
- https://doi.org/10.1016/j.jare.2020.08.012