Back to Search
Start Over
1,2‐Benzothiazine Derivatives from Sulfonimidamides by Metal‐Catalyzed Annulation Reactions in Solution and under Solvent‐Free Mechanochemical Conditions.
- Source :
-
Advanced Synthesis & Catalysis . 3/2/2021, Vol. 363 Issue 5, p1322-1329. 8p. - Publication Year :
- 2021
-
Abstract
- Three‐dimensional aza‐analogues of 1,2‐benzothiazine 1,1‐dioxides have been prepared from sulfonimidamides. Two different protocols are presented. The first is a rhodium‐catalyzed annulation reaction with α‐sulfonyloxyketones leading to 4‐unsubstituted benzothiazine derivatives. By selective bromination with NBS the heterocyclic ring can further be functionalized. In the second approach, an iridium catalyst is applied under solvent‐free mechanochemical conditions providing products with 3,4‐disubstituted thiazine rings from diazoketo esters and diazoketo sulfones. [ABSTRACT FROM AUTHOR]
- Subjects :
- *ANNULATION
*IRIDIUM catalysts
*BENZOTHIAZINE
*BROMINATION
*CATALYSIS
*SULFONES
Subjects
Details
- Language :
- English
- ISSN :
- 16154150
- Volume :
- 363
- Issue :
- 5
- Database :
- Academic Search Index
- Journal :
- Advanced Synthesis & Catalysis
- Publication Type :
- Academic Journal
- Accession number :
- 149048730
- Full Text :
- https://doi.org/10.1002/adsc.202001505