Outcome of liver transplantation in adult population in Bulgaria.

Liver transplantation is treatment of choice for patients with end stage liver disease (ESLD). However, due to high surgical risk and risk of complications from the immunosuppressive agents pose significant challenges in transplanting setting. The aim of our study was to evaluate survival after liver transplantation. In this paper survival analysis is used to determine the prognostic significance of age of the recipient at the time of transplantation, sex, Model for End-Stage Liver Disease (MELD) score, complications after transplantation and treatment of complications, and to model the time it takes for death. The data is obtained from 41 patients, who have been transplanted at the University Hospital "Lozenetz", Sofia, Bulgaria in the period 2006-2019. For estimating event (death) free survival rate the Kaplan–Meier method is used. Time to event is calculated as the time from study entry to first event or date of last contact. Multivariate analysis is conducted by using Cox proportional hazards regression. [ABSTRACT FROM AUTHOR]