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Tea polysaccharides from Camellia sinensis: chemical analysis, structural characterization, and inhibition of HeLa cells activity.
- Source :
-
International Journal of Polymer Analysis & Characterization . Apr2021, Vol. 26 Issue 3, p240-252. 13p. - Publication Year :
- 2021
-
Abstract
- Tea polysaccharides (TPS) were analyzed and characterized by HPAEC, GPC, FT-IR, AFM, HSQC, and HMBC NMR as well as methylation. The TPS mainly consisted of neutral (F0, F0.2, and F0.3) and acidic polysaccharides (F0.1) rich in glucuronic acid. Moreover, anti-proliferative activity of the TPS on HeLa cells was investigated. It was found that F0 exhibited the highest inhibition rate (36.7%) with 200 µg/ml treatment for 48 h. Structural characterization revealed that F0 had a backbone chain of (1→4)-β-d-Glcp, (1→6)-α-d-Galp, (1→2)-α-l-Rhap and (1→2,4)-α-l-Rhap residues with (1→6)-α-d-Galp and acetyl group side chains. [ABSTRACT FROM AUTHOR]
- Subjects :
- *HELA cells
*TEA
*ANALYTICAL chemistry
*POLYSACCHARIDES
*GLUCURONIC acid
Subjects
Details
- Language :
- English
- ISSN :
- 1023666X
- Volume :
- 26
- Issue :
- 3
- Database :
- Academic Search Index
- Journal :
- International Journal of Polymer Analysis & Characterization
- Publication Type :
- Academic Journal
- Accession number :
- 149306951
- Full Text :
- https://doi.org/10.1080/1023666X.2021.1877957