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Microbial dark matter coming to light: challenges and opportunities.
- Source :
-
National Science Review . Mar2021, Vol. 8 Issue 3, p1-5. 5p. - Publication Year :
- 2021
-
Abstract
- Notably, single-amplified genomes (SAGs) and metagenome-assembled genomes (MAGs) obtained from single-cell genomic and metagenomic approaches, respectively, have become the most effective methods that enable organism-level genomic analysis of complex microbial ecosystems without the need for cultivation, which brings lighttoMDM. Hug et al. used more than 1000 MDM genomes, together with public genomic data,toinferthetreeoflifeanddescribed a hyper-diverse clade of MDM termed the Candidate Phyla Radiation (CPR), subdividing the domain Bacteria [4]. The study of MDM is still in its infancy and further exploration of MDM will continue to provide unanticipated and excitinganswersabouttheevolutionand roles of MDM in nature. This is so-called Microbial Dark Matter (MDM): the enormous diversity of yet-uncultivated microbes that microbiologists can only study by using cultivation-independent techniques. [Extracted from the article]
- Subjects :
- *DARK matter
*SCIENTIFIC communication
*GENOMICS
*GENES
*MICROORGANISMS
Subjects
Details
- Language :
- English
- ISSN :
- 20955138
- Volume :
- 8
- Issue :
- 3
- Database :
- Academic Search Index
- Journal :
- National Science Review
- Publication Type :
- Academic Journal
- Accession number :
- 149415000
- Full Text :
- https://doi.org/10.1093/nsr/nwaa280