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Arginine methyltransferase PRMT5 negatively regulates cGAS-mediated antiviral immune response.

Authors :
Dapeng Ma
Min Yang
Qiushi Wang
Caiyu Sun
Hongbiao Shi
Weiqiang Jing
Yuxuan Bi
Xuecheng Shen
Xiaomin Ma
Zhenzhi Qin
Yueke Lin
Lihui Zhu
Yunxue Zhao
Yeping Cheng
Lihui Han
Source :
Science Advances. 3/24/2021, Vol. 7` Issue 13, p1-14. 14p.
Publication Year :
2021

Abstract

The article presents findings of the study related to Arginine methyltransferase PRMT5 negatively regulates cGAS-mediated antiviral immune response. It mentions that findings revealed an essential regulatory effect of PRMT5 on cGAS mediated antiviral immune response and provided a promising potential antiviral strategy by modulating PRMT5.

Details

Language :
English
ISSN :
23752548
Volume :
7`
Issue :
13
Database :
Academic Search Index
Journal :
Science Advances
Publication Type :
Academic Journal
Accession number :
149584599
Full Text :
https://doi.org/10.1126/sciadv.abc1834