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Flavonol-based small-molecule fluorescent probes.

Authors :
Qin, Tianyi
Liu, Bin
Xu, Zhongyong
Yao, Guangkai
Xu, Hanhong
Zhao, Chen
Source :
Sensors & Actuators B: Chemical. Jun2021, Vol. 336, pN.PAG-N.PAG. 1p.
Publication Year :
2021

Abstract

[Display omitted] • The flavonol-based small-molecule fluorescent probes are reviewed. • ƒÜ The unique photophysical process of flavonol and its advantages in probe design are introduced. • ƒÜ The design mechanism of flavonol-based fluorescent probes has been discussed and categorized. • ƒÜ The sensing performances and applications of probes are summarized. Flavonols, named as 3-hydroxyl-2-phenyl-1-benzopyran-4-one, are important natural botanical functional pigments widely distributing in fruits, vegetables, and flowers. Owing to intramolecular hydrogen bond, the flavonols can undergo the excited-state intramolecular proton transfer (ESIPT) process upon irradiation, leading to unique environmental-sensitive dual emissions, which makes flavonol an ideal fluorophore skeleton for probe design. In this paper, we summarized the recent progress of flavonol-based small-molecule fluorescent probes for diverse sensing applications, including detection of anions, cations, reactive biological species, proteins, DNAs, environmental hazards, and microenvironmental factors. This review highlighted the basic characteristics of flavonol probes in the respect of design principles, photophysical processes, sensing mechanism, sensing performances, and biological applications. The present review article aims to offer a comprehensive summary for researchers to inspire new probe design, and push forward the advancement of flavonol-based fluorescent probes. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
09254005
Volume :
336
Database :
Academic Search Index
Journal :
Sensors & Actuators B: Chemical
Publication Type :
Academic Journal
Accession number :
149712077
Full Text :
https://doi.org/10.1016/j.snb.2021.129718