Counting the cost of a cold-blooded life: Metabolomics of cold acclimation.

This article focuses on metabolomics of cold acclimation. Plants, like poikilothermic animals, face a requisite environmental challenge: they must maintain balanced cellular metabolism, and cell and organelle integrity, in the face of changes in temperature that may be both rapid and extreme. One of the best-characterized temperature responses is the ability of plants to increase their freezing tolerance in Eesponse to a period of low, nonfreezing temperatures before the onset of winter-cold acclimation (CA).