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Association between serum apolipoprotein B and diabetic retinopathy in type 2 diabetic patients.
- Source :
-
Scientific Journal of Al-Azhar Medical Faculty, Girls . Jan-Mar2021, Vol. 5 Issue 1, p73-77. 5p. - Publication Year :
- 2021
-
Abstract
- Background Diabetic retinopathy (DR) is a major microvascular complication of diabetes. Aim of the work To study the association between serum apolipoprotein B (Apo-B) and DR in type 2 diabetes. Patients and methods This comparative study was conductedon75patients with type2diabetes recruited from the Endocrinology and Ophthalmology Departments of Al-Zahraa University Hospital. They were divided into three groups according to DR grading: group A included 31 patients without DR, group B included 27 patients with nonproliferativeDR, and group C included 17 patients with proliferative DR. Detailed history, clinical examination, and anthropometric measurementswere assessed for all selected patients. Fasting and 2-h postprandial blood glucose levels, glycosylated hemoglobin, total cholesterol (CHO), triglycerides (TG), lowdensity lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), and Apo-B were measured. Fundus examination was done for all participants. Results CHO, TGs, LDL-C, and Apo-B were statistically significantly higher in group C followed by group B and then group A. However, HDL-C was statistically significantly lower in group C followed by group B and then group A. A significant positive correlation was found between DR on one hand and age, diabetes duration, systolic blood pressure, diastolic blood pressure, glycosylated hemoglobin, CHO, TGs, LDL-C, and Apo-B on the other hand. DR correlated negatively with HDL-C. Conclusion Serum Apo-B levels may be a strong biomarker for DR than traditional lipids. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 11102381
- Volume :
- 5
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- Scientific Journal of Al-Azhar Medical Faculty, Girls
- Publication Type :
- Academic Journal
- Accession number :
- 150119834
- Full Text :
- https://doi.org/10.4103/sjamf.sjamf_25_21