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Furan fragment isomerized andirobin-type limonoids from the stem barks of Khaya senegalensis.
- Source :
-
Journal of Asian Natural Products Research . May2021, Vol. 23 Issue 5, p498-503. 6p. - Publication Year :
- 2021
-
Abstract
- A new andirobin-type limonoid with modified furan ring, khaysenelide K (1), together with a known analogue (2), was isolated from the stem barks of Khaya senegalensis. The structure and absolute configuration of 1 were elucidated by a combination of 1D and 2D NMR, HRESIMS, and single-crystal X-ray diffraction using mirror Cu-Kα radiation. Compound 1 showed moderate NO inhibitory activity in LPS-activated RAW 264.7 macrophages with IC50 value of 27.74 ± 0.68 μM. [ABSTRACT FROM AUTHOR]
- Subjects :
- *X-rays
*IN vitro studies
*HIGH performance liquid chromatography
*MAGNETIC resonance imaging
*MACROPHAGES
*HYDROCARBONS
*PLANT stems
*BARK
*CRYSTALLOGRAPHY
*RESEARCH funding
*MOLECULAR structure
*NITRIC oxide
*PLANT extracts
*STATISTICAL correlation
*CELL surface antigens
*ETHANOL
*IMMUNODIAGNOSIS
Subjects
Details
- Language :
- English
- ISSN :
- 10286020
- Volume :
- 23
- Issue :
- 5
- Database :
- Academic Search Index
- Journal :
- Journal of Asian Natural Products Research
- Publication Type :
- Academic Journal
- Accession number :
- 150123755
- Full Text :
- https://doi.org/10.1080/10286020.2020.1767080