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Effects of amino proton and denticity of quinoline-pyridine based dyes on Cd2+ and Zn2+ fluorescence sensing properties.
- Source :
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Journal of Photochemistry & Photobiology A: Chemistry . Jun2021, Vol. 415, pN.PAG-N.PAG. 1p. - Publication Year :
- 2021
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Abstract
- [Display omitted] • A novel series of quinoline-pyridine conjugated compounds were synthesized. • The effects of amino protons and denticity to metal were studied. • The absence of amino proton increases the Cd2+/Zn2+ selectivity. • The increase of N atoms increases the binding to Cd2+ greater than Zn2+. • The compounds were applicable for detecting Cd2+ in aqueous media and cell imaging. Zn2+ and Cd2+ are d10 metal ions with very different toxicity level but similar binding properties to most organic ligands. Herein, a series of quinoline-pyridine conjugates are synthesized and evaluated for binding properties on both metal ions. The effects of amino protons and number of N-donor atoms on the ligands binding to Cd2+ and Zn2+ were studied by UV–vis titration in aqueous solution. The association constant for Cd2+ is affected by amino protons and denticity of the ligands greater than that of Zn2+. As the results, the Cd2+/Zn2+ binding ratio can be tuned by the ligand design. L6, the ligand with 6 N atoms without the proton, exhibits the highest Cd2+/Zn2+ binding ratio with fluorescence enhancement at 480 nm. The ligand can be used for detecting Cd2+ with the detection limit of 69 nM in aqueous solution and monitoring Cd2+ within cells at the concentration range of 0.1−10 μM. [ABSTRACT FROM AUTHOR]
- Subjects :
- *ATOMIC number
*PROTONS
*FLUORESCENCE
*CELL imaging
*BINDING constant
Subjects
Details
- Language :
- English
- ISSN :
- 10106030
- Volume :
- 415
- Database :
- Academic Search Index
- Journal :
- Journal of Photochemistry & Photobiology A: Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 150291278
- Full Text :
- https://doi.org/10.1016/j.jphotochem.2021.113307