Basophil activation and serum IL‐5 levels as possible monitor biomarkers in severe eosinophilic asthma patients treated with anti‐IL‐5 drugs.

Keywords: asthma; basophil; eosinophils; interleukins EN asthma basophil eosinophils interleukins 1569 1571 3 05/17/21 20210501 NES 210501 Interleukin-5 (IL-5) is one of the main cytokine involved in the pathogenesis of eosinophilic asthma (EA) and exerts pleiotropic activities on various target cells expressing its receptor, including eosinophils and basophils. Basophil activation and serum IL-5 levels as possible monitor biomarkers in severe eosinophilic asthma patients treated with anti-IL-5 drugs Allergy Asthma Clin Immunol. 2020; 22 (16): 27. 9 Siegmund R, Vogelsang H, Machnik A, Herrmann D. Surface membrane antigen alteration on blood basophils in patients with hymenoptera venom allergy under immunotherapy. [Extracted from the article]