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Evidence of robust memory T‐cell responses in patients with chronic myeloproliferative neoplasms following infection with severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2).

Authors :
Harrington, Patrick
Harrison, Claire N.
Dillon, Richard
Radia, Deepti H.
Rezvani, Katayoun
Raj, Kavita
Woodley, Claire
Curto‐Garcia, Natalia
O'Sullivan, Jennifer
Saunders, Jamie
Kordasti, Shahram
Ali, Sahra
Lavallade, Hugues
McLornan, Donal P.
Source :
British Journal of Haematology. May2021, Vol. 193 Issue 4, p692-696. 5p.
Publication Year :
2021

Abstract

Evidence of robust memory T-cell responses in patients with chronic myeloproliferative neoplasms following infection with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) Keywords: COVID-19; immunity; T cell; myeloproliferative neoplasm; CML EN COVID-19 immunity T cell myeloproliferative neoplasm CML 692 696 5 05/17/21 20210515 NES 210515 Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), a novel coronavirus, has led to very significant global healthcare challenges. Patients with chronic MPN without detectable antibodies had a T-cell response that was broadly equivalent in many areas to that seen in those with detectable anti-SARS-CoV-2 antibodies. For the first time, we have demonstrated that patients with chronic MPN can mount functional memory T-cell responses following natural SARS-CoV-2 exposure. [Extracted from the article]

Details

Language :
English
ISSN :
00071048
Volume :
193
Issue :
4
Database :
Academic Search Index
Journal :
British Journal of Haematology
Publication Type :
Academic Journal
Accession number :
150291773
Full Text :
https://doi.org/10.1111/bjh.17402