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A new coumarin based Schiff base fluorescence probe for zinc ion.
- Source :
-
Tetrahedron . May2021, Vol. 88, pN.PAG-N.PAG. 1p. - Publication Year :
- 2021
-
Abstract
- Herein, a novel coumarin-based fluorescent probe (FS3) was designed, synthesized, and characterized. It exhibited significant fluorescence quenching in the presence of Zn2+ ions. Just a minor alteration occurred in the fluorescence intensity of FS3 in the presence of other metals studied. The limit of detection for the determination of Zn2+ by FS3 was calculated to be 3.43 × 10−9 M. Since the Job's graph of 1/(F 0 –F) and 1/[Zn2+] had a linear fit, it was determined that the binding stoichiometry between the FS3 and Zn2+ was 1:1. The association constant of the system was found to be 2.39 × 104 M−1 and confirmed by ESI-MS and FT-IR. It was demonstrated that the developed highly reversible sensor system works by performing real sample analysis. Moreover, the FS3 which has shown no toxicity and displayed a strong fluorescence image will act as an efficient and non-destructive sensor for the determination of Zn2+ in living organisms. [Display omitted] • A novel coumarin-based fluorescent probe (FS3) was designed, synthesized, and characterized. • Significant fluorescence quenching was observed in the presence of Zn2+ ions. • Stoichiometry between the FS3 and Zn2+ was 1:1. • The association constant for Zn2+ binding with FS3 was found to be 2.39 × 104 M−1 according to the Benesi-Hildebrand method. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00404020
- Volume :
- 88
- Database :
- Academic Search Index
- Journal :
- Tetrahedron
- Publication Type :
- Academic Journal
- Accession number :
- 150411091
- Full Text :
- https://doi.org/10.1016/j.tet.2021.132127