Metabolic Reprogramming in Congenital Cyanotic Heart Disease: Another Fight in Puberty?

Congenital heart disease, hypoxia, metabolism, puberty, pulmonary heart disease, pulmonary hypertension HIF-1 indicates hypoxia-inducible factor-1 ; HOX, hypoxia; incl., including; LV, left ventricle; and RV, right ventricle. Keywords: congenital heart disease; hypoxia; metabolism; puberty; pulmonary heart disease; pulmonary hypertension EN congenital heart disease hypoxia metabolism puberty pulmonary heart disease pulmonary hypertension 2273 2276 4 06/10/21 20210608 NES 210608 B Article, see p 2254 b Congenital heart diseases are complex anatomic malformations that lead to molecular and structural adaptations to compensate for the resulting hemodynamic disturbances. [Extracted from the article]