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Oral therapy adherence and satisfaction in patients with multiple myeloma.
- Source :
-
Annals of Hematology . Jul2021, Vol. 100 Issue 7, p1803-1813. 11p. - Publication Year :
- 2021
-
Abstract
- The transition to oral therapies in patients with multiple myeloma (MM) offers potential benefits to patients; however, they must self-manage their medication and adherence plays an important role in patient care. It has been shown that patient satisfaction with their medication has a strong positive correlation with adherence in chronic diseases. The aim of this study was to estimate adherence rate of oral antimyeloma therapies and to identify risk factors for medication non-adherence. This observational, prospective, and multicentre survey based on a self-report questionnaire enrolled MM patients with at least 3 months of oral therapy. The 6-item Girerd scale and the medication possession ratio (MPR) were used for measuring medication adherence and the SATMED-Q® questionnaire was used for measuring satisfaction. An analysis of risk factors for non-adherence to oral therapy was performed using univariate analysis. A total of 101 patients participated in the survey, yielding a response rate of 87%. The prevalence of adherence to oral antimyeloma therapy was estimated at 51.5% using the Girerd questionnaire. According to the MPR, adherence was evaluated at 96% (i.e. MPR ≥ 0.80). Both methods combined, adherence was estimated at 50.5%. One risk factor for medication non-adherence was identified: Eastern Cooperative Oncology Group Performance Status > 2 (p = 0.007). One predictive factor for high medication adherence was identified: high satisfaction with treatment (p = 0.01). Identifying patients at higher risk for non-adherence allows clinical pharmacists to personalise therapeutic information and education and to improve the quality of healthcare overall. [ABSTRACT FROM AUTHOR]
- Subjects :
- *PATIENT compliance
*PATIENT satisfaction
*MULTIPLE myeloma
*UNIVARIATE analysis
*FACTOR analysis
*HOSPITAL statistics
*THERAPEUTIC use of antineoplastic agents
*RESEARCH
*FERRANS & Powers Quality of Life Index
*ACADEMIC medical centers
*SPECIALTY hospitals
*CROSS-sectional method
*ORAL drug administration
*RESEARCH methodology
*ANTINEOPLASTIC agents
*SATISFACTION
*MEDICAL cooperation
*EVALUATION research
*SOCIOECONOMIC factors
*COMPARATIVE studies
*DRUGS
*PSYCHOLOGY of caregivers
*QUESTIONNAIRES
*LONGITUDINAL method
Subjects
Details
- Language :
- English
- ISSN :
- 09395555
- Volume :
- 100
- Issue :
- 7
- Database :
- Academic Search Index
- Journal :
- Annals of Hematology
- Publication Type :
- Academic Journal
- Accession number :
- 150853642
- Full Text :
- https://doi.org/10.1007/s00277-021-04543-7