Back to Search
Start Over
Synthesis and in vitro anticancer activities of biotinylated derivatives of glaucocalyxin A and oridonin.
- Source :
-
Journal of Asian Natural Products Research . Jul2021, Vol. 23 Issue 7, p703-711. 9p. - Publication Year :
- 2021
-
Abstract
- Fourteen glaucocalyxin A biotinylated derivatives, one glaucocalyxin C biotinylated derivative, and two oridonin biotinylated derivatives were designed and synthesized. Their structures were confirmed from 1H NMR, 13C NMR and HRMS data. The derivatives were evaluated for cytotoxic activities against lung (A549), cervical cancer cell line HeLa derivative (KB), multidrug-resistant KB subline (KB-VIN), triple-negative breast (MDA-MB-231), and estrogen receptor-positive breast (MCF-7) cancer cell lines. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 10286020
- Volume :
- 23
- Issue :
- 7
- Database :
- Academic Search Index
- Journal :
- Journal of Asian Natural Products Research
- Publication Type :
- Academic Journal
- Accession number :
- 151159721
- Full Text :
- https://doi.org/10.1080/10286020.2020.1760851