Effect of Fe3O4 concentration on 3D gel-printed Fe3O4/CaSiO3 composite scaffolds for bone engineering.

In this study, porous calcium silicate (CaSiO 3) scaffolds were prepared by 3D gel-printing (3DGP) method and Fe 3 O 4 water-based magnetic fluids (WMFs) were prepared by phacoemulsification compound chemical coprecipitation method. Fe 3 O 4 WMFs were coated on CaSiO 3 scaffolds surface to prepare Fe 3 O 4 /CaSiO 3 composite scaffolds. The effect of WMFs with different Fe 3 O 4 concentrations on porous CaSiO 3 scaffolds was studied. The composition and morphological characteristics of porous scaffolds were analyzed by using scanning electron microscope (SEM) and energy dispersive spectrometer (EDS) analysis. The magnetic properties were tested by vibrating sample magnetometer (VSM). The stability of Fe 3 O 4 WMFs coatings and the degradability of composite scaffolds were tested by immersing them in simulated body fluid (SBF). The results show that when Fe 3 O 4 concentration was 5.4% (w/v), the composite scaffolds had the highest saturation magnetization of 69.6 emu/g and the best stability in dynamic SBF. It is obviously that Fe 3 O 4 WMFs coatings can be used for bone tissue engineering scaffolds repairing. [ABSTRACT FROM AUTHOR]