Multidimensional separations in analytical chemistry.

The article presents information on multidimensional separations in analytical chemistry. Conventional, heart-cut multidimensional separations are valuable when extra resolution is needed in the examination of a small segment of peaks in a complex chromatogram. Prior knowledge of the sample composition is always beneficial. In comprehensive multidimensional separation techniques, the entire sample, not just a part of it, is subjected to different separations. Separation techniques that utilize more than two dimensions can certainly be expected in the future.