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Myasthenic crisis following SARS-CoV-2 infection and delayed virus clearance in a patient treated with rituximab: clinical course and 6-month follow-up.

Authors :
Wanschitz, Julia V.
Kaml, Manuela
Pfausler, Bettina
Helbok, Raimund
Wildner, Sophie
Widmann, Gerlig
Sahanic, Sabina
Deisenhammer, Florian
Löscher, Wolfgang N.
Reindl, Markus
Löffler-Ragg, Judith
Beer, Ronny
Source :
Journal of Neurology. Aug2021, Vol. 268 Issue 8, p2700-2702. 3p.
Publication Year :
2021

Abstract

Regarding cardio-pulmonary health, the patient was followed within the prospective observational multicenter COVID study to investigate long-term sequelae in patients hospitalized for SARS-CoV-2 infection (NCT 04416100) that was approved by the local ethics committee (EK 1103/2020). Maintenance of standard immunosuppressive treatment is recommended in mild-to-moderate disease [[7]]; however, information about the management and outcome of patients with severe generalized MG treated with immune-depleting agents such as rituximab is still limited. Dear Sirs, Novel Corona Virus Disease 2019 (COVID-19) poses an unpredictable risk for patients with myasthenia gravis (MG) due to potentially additive effects of bulbar and respiratory muscle weakness and viral lung affection [[1]]. [Extracted from the article]

Details

Language :
English
ISSN :
03405354
Volume :
268
Issue :
8
Database :
Academic Search Index
Journal :
Journal of Neurology
Publication Type :
Academic Journal
Accession number :
151470259
Full Text :
https://doi.org/10.1007/s00415-020-10310-x