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Association of cognitive impairment with sleep quality, depression and cardiometabolic risk factors in individuals with type 2 diabetes mellitus: A cross sectional study.
- Source :
-
Journal of Diabetes & its Complications . Aug2021, Vol. 35 Issue 8, pN.PAG-N.PAG. 1p. - Publication Year :
- 2021
-
Abstract
- <bold>Aim: </bold>The aim of this study was to evaluate the association of cognitive impairment with sleep quality, depression, and cardiometabolic risk factors among participants with type 2 diabetes mellitus.<bold>Methods: </bold>Subjects underwent clinical interview to capture socio-demographic details, medical history, sleep quality, presence of depression, along with anthropometric and biochemical measurements. A detailed neuropsychological assessment [Montreal cognitive assessment scale (MoCA), Trail making A and B, Digit span, Spatial span, Letter Number Sequencing] was done. Cognitive impairment was defined as MoCA score of <23.<bold>Results: </bold>Participants (n=250, 50% women, 63.6% middle-age) had a mean (±SD) age of 53.6 (±9.1) years and HbA1c of 55.1±6.8mmol/mol (7.2±0.6%). Cognitive impairment was present in 57 (22.8%) participants. In the middle-age subgroup, cognitive impairment was higher (23.9%) than those in the fourth decade (6.3%), but comparable (24.0%) to the older age (60-70years) individuals. Diabetes-related vascular complications [Odds ratio (95% CI) 2.03 (1.05, 3.94)]; hypertension [2.00 (1.04, 3.84)], depression [2.37 (1.24, 4.55)] and lower education [2.73 (1.42, 5.23)] had a significant association with cognitive impairment on multivariate logistic regression analysis.<bold>Conclusion: </bold>The high burden of cognitive impairment calls for an urgent need to establish longitudinal cohorts in midlife to understand this population's cognitive trajectories and see the influence of various bio-psychosocial variables. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 10568727
- Volume :
- 35
- Issue :
- 8
- Database :
- Academic Search Index
- Journal :
- Journal of Diabetes & its Complications
- Publication Type :
- Academic Journal
- Accession number :
- 151491618
- Full Text :
- https://doi.org/10.1016/j.jdiacomp.2021.107970