Back to Search
Start Over
COVID-19: from an acute to chronic disease? Potential long-term health consequences.
- Source :
-
Critical Reviews in Clinical Laboratory Sciences . Aug2021, Vol. 58 Issue 5, p297-310. 14p. - Publication Year :
- 2021
-
Abstract
- Coronavirus disease 2019 (COVID-19) is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Despite pulmonary impairments being the most prevalent, extra-pulmonary manifestations of COVID-19 are abundant. Confirmed COVID-19 cases have now surpassed 57.8 million worldwide as of 22 November 2020. With estimated case fatality rates (number of deaths from COVID-19 divided by number of confirmed COVID-19 cases) varying between 1 and 7%, there will be a large population of recovered COVID-19 patients that may acquire a multitude of long-term health consequences. While the multi-organ manifestations of COVID-19 are now well-documented, the potential long-term implications of these manifestations remain to be uncovered. In this review, we turn to previous similar coronaviruses (i.e. SARS-CoV-1 and Middle East respiratory syndrome coronavirus [MERS-CoV]) in combination with known health implications of SARS-CoV-2 infection to predict potential long-term effects of COVID-19, including pulmonary, cardiovascular, hematologic, renal, central nervous system, gastrointestinal, and psychosocial manifestations, in addition to the well-known post-intensive care syndrome. It is necessary to monitor COVID-19 patients after discharge to understand the breadth and severity of long-term effects. This can be accomplished by repurposing or initiating large cohort studies to not only focus on the long-term consequences of SARS-CoV-2 infection, but also on acquired immune function as well as ethno-racial group and household income disparities in COVID-19 cases and hospitalizations. The future for COVID-19 survivors remains uncertain, and if this virus circulates among us for years to come, long-term effects may accumulate exponentially. [ABSTRACT FROM AUTHOR]
- Subjects :
- *MENTAL illness risk factors
*CENTRAL nervous system diseases
*CARDIOVASCULAR diseases risk factors
*INTENSIVE care units
*COVID-19
*MIDDLE East respiratory syndrome
*LUNG diseases
*PSYCHOSES
*GASTROINTESTINAL diseases
*NEUROLOGIC manifestations of general diseases
*BLOOD diseases
*SARS disease
*ACUTE kidney failure
*DISEASE risk factors
*DISEASE complications
Subjects
Details
- Language :
- English
- ISSN :
- 10408363
- Volume :
- 58
- Issue :
- 5
- Database :
- Academic Search Index
- Journal :
- Critical Reviews in Clinical Laboratory Sciences
- Publication Type :
- Academic Journal
- Accession number :
- 151582256
- Full Text :
- https://doi.org/10.1080/10408363.2020.1860895