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Portable Electrochemiluminescence Platform With Laser-Induced Graphene-Based U-Shaped Bipolar Electrode for Selective Sensing of Various Analytes.
- Source :
-
IEEE Transactions on Electron Devices . May2021, Vol. 68 Issue 5, p2447-2454. 8p. - Publication Year :
- 2021
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Abstract
- In recent years, rising need of microfluidics-based point-of-care devices has led to cost-effective solutions at or near the location of patients. With this motivation, herein, laser-induced graphene (LIG)-based electrochemiluminescence (ECL) system loaded with U-shaped bipolar electrode (U-BPE) has been developed and its application for enzymeless sensing of various biomarkers has been validated. Low-cost and easily available flexible polyimide (PI) sheet has been effectively used for the fabrication of LIG U-BPE ECL device. With optimized speed and power, the ablation of CO2 laser on PI has been carried out to create graphenized driving electrodes and U-BPE in a single step. A cost-effective and portable 3-D printed platform has been developed for image sensing of ECL signals. The bulky power supply was effectively replaced by a dual-functional android smartphone to provide power to the LIG U-BPE ECL sensor and to capture the ECL signals. With this mini-platform, determination of various analytes, such as H2O2, D-glucose, lactate, and choline, has been accomplished in a linear range of 0.1–50, 0.1–70, 1–100, and 1– 100 μM with limit of detection (LOD) of 4.36, 2.51, 5.32, and 4.01 μ M, respectively. An interference study has been performed and it was found that after adding interfering compounds in analytes, ECL signal intensity was reduced to less than 5%. Hence, it was proven that LIG U-BPE ECL device was very selective to different analytes concerning to their voltages. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00189383
- Volume :
- 68
- Issue :
- 5
- Database :
- Academic Search Index
- Journal :
- IEEE Transactions on Electron Devices
- Publication Type :
- Academic Journal
- Accession number :
- 151778163
- Full Text :
- https://doi.org/10.1109/TED.2021.3066083