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An Overview On Anti-Ages Therapy: Mini Review.

Authors :
Ishrat, Nayab
Ahmad, Saheem
Srivastava, Arvind K.
Mujeeb, Farina
Mahdi, Abbas Ali
Source :
Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research). 2021, Vol. 12 Issue 4, p845-861. 17p. 1 Diagram.
Publication Year :
2021

Abstract

Non-enzymatic glycosylation is glycation between protein and reducing sugar transforming into the formation of advanced glycation end products (AGEs). Many of the epidemiological studies have demonstrated a strong correlation between the formation of AGEs with the pathogenesis of several chronic complications like inflammation, diabetes, nephropathy, retinopathy, neuropathy, atherosclerosis, and cancer. Besides, considering AGEs as lethal components, there are still very fragmentary research on the discovery and development of AGEs inhibitors. One of the causes may be the lack of awareness about the importance of anti-AGEs in the said disorders. The discovery and investigation of compounds with an AGEs inhibitor activity may offer a potential therapeutic approach for the prevention of such several pathogenic complications. The present review summarizes research on anti-AGEs products in chronic complications like inflammation, atherosclerosis, diabetes, cancer and several other disorders. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
09753583
Volume :
12
Issue :
4
Database :
Academic Search Index
Journal :
Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research)
Publication Type :
Academic Journal
Accession number :
151994386