Effects of Tai Chi or Conventional Exercise on Central Obesity in Middle-Aged and Older Adults : A Three-Group Randomized Controlled Trial.

<bold>Background: </bold>Central obesity is a major manifestation of metabolic syndrome, which is a common health problem in middle-aged and older adults.<bold>Objective: </bold>To examine the therapeutic efficacy of tai chi for management of central obesity.<bold>Design: </bold>Randomized, controlled, assessor-blinded trial. (ClinicalTrials.gov: NCT03107741).<bold>Setting: </bold>A single research site in Hong Kong between 27 February 2016 and 28 February 2019.<bold>Participants: </bold>Adults aged 50 years or older with central obesity.<bold>Intervention: </bold>543 participants were randomly assigned in a 1:1:1 ratio to a control group with no exercise intervention (n = 181), conventional exercise consisting of aerobic exercise and strength training (EX group) (n = 181), and a tai chi group (TC group) (n = 181). Interventions lasted 12 weeks.<bold>Measurements: </bold>Outcomes were assessed at baseline, week 12, and week 38. The primary outcome was waist circumference (WC). Secondary outcomes were body weight; body mass index; high-density lipoprotein cholesterol (HDL-C), triglyceride, and fasting plasma glucose levels; blood pressure; and incidence of remission of central obesity.<bold>Results: </bold>The adjusted mean difference in WC from baseline to week 12 in the control group was 0.8 cm (95% CI, -4.1 to 5.7 cm). Both intervention groups showed reductions in WC relative to control (adjusted mean differences: TC group vs. control, -1.8 cm [CI, -2.3 to -1.4 cm]; P < 0.001; EX group vs. control: -1.3 cm [CI, -1.8 to -0.9 cm]; P < 0.001); both intervention groups also showed reductions in body weight (P < 0.05) and attenuation of the decrease in HDL-C level relative to the control group. The favorable changes in WC and body weight were maintained in both the TC and EX groups, whereas the beneficial effect on HDL-C was only maintained in the TC group at week 38.<bold>Limitations: </bold>High attrition and no dietary intervention.<bold>Conclusion: </bold>Tai chi is an effective approach to reduce WC in adults with central obesity aged 50 years or older.<bold>Primary Funding Source: </bold>Health and Medical Research Fund. [ABSTRACT FROM AUTHOR]