LAMOTRIGINE MAY INCREASE RISK OF ARRYTHMIAS.

The article reports that Lamotrigine (Lamictal) has been used to treat epilepsy and bipolar disorder since its approval in 1994.Topisc discussed include the Food and Drug Administration (FDA) has been evaluating in vitro studies of lamotrigine's effect on the heart; and FDA has issued a Drug Safety Communication to warn that lamotrigine has the potential to increase the risk of arrythmias in patients with heart disease.