Back to Search
Start Over
Analysis of Multiple Bands on Serum Protein Immunofixation Electrophoresis: Challenge in Interpretation of Clonality in a Patient with Light Chain–Predominant Multiple Myeloma.
- Source :
-
Laboratory Medicine . Sep2021, Vol. 52 Issue 5, p503-508. 6p. - Publication Year :
- 2021
-
Abstract
- Sera from patients with multiple myeloma usually display a single monoclonal immunoglobulin band on serum protein immunofixation electrophoresis. Multiple bands may be seen if the myeloma is bi- or triclonal or if the monoclonal immunoglobulin has rheumatoid factor activity. We describe a patient with light chain–predominant IgA lambda myeloma; the patient's serum displayed 2 spatially distinct bands reacting for alpha heavy and lambda light chains. The methods used to establish monoclonality are addressed. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00075027
- Volume :
- 52
- Issue :
- 5
- Database :
- Academic Search Index
- Journal :
- Laboratory Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 152287129
- Full Text :
- https://doi.org/10.1093/labmed/lmab001