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SARS-CoV-2 (Covid-19) vaccines structure, mechanisms and effectiveness: A review.

Authors :
Fathizadeh, Hadis
Afshar, Saman
Masoudi, Mahmood Reza
Gholizadeh, Pourya
Asgharzadeh, Mohammad
Ganbarov, Khudaverdi
Köse, Şükran
Yousefi, Mehdi
Kafil, Hossein Samadi
Source :
International Journal of Biological Macromolecules. Oct2021, Vol. 188, p740-750. 11p.
Publication Year :
2021

Abstract

The world has been suffering from COVID-19 disease for more than a year, and it still has a high mortality rate. In addition to the need to minimize transmission of the virus through non-pharmacological measures such as the use of masks and social distance, many efforts are being made to develop a variety of vaccines to prevent the disease worldwide. So far, several vaccines have reached the final stages of safety and efficacy in various phases of clinical trials, and some, such as Moderna/NIAID and BioNTech/Pfizer, have reported very high safety and protection. The important point is that comparing different vaccines is not easy because there is no set standard for measuring neutralization. In this study, we have reviewed the common platforms of COVID-19 vaccines and tried to present the latest reports on the effectiveness of these vaccines. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
01418130
Volume :
188
Database :
Academic Search Index
Journal :
International Journal of Biological Macromolecules
Publication Type :
Academic Journal
Accession number :
152426803
Full Text :
https://doi.org/10.1016/j.ijbiomac.2021.08.076