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Anemia at Intensive Care Unit Admission and Hospital Mortality Among Patients at a Referral Hospital in Malawi.
- Source :
-
American Surgeon . Aug2021, Vol. 87 Issue 8, p1334-1340. 7p. - Publication Year :
- 2021
-
Abstract
- <bold>Background: </bold>Anemia is associated with intensive care unit (ICU) outcomes, but data describing this association in sub-Saharan Africa are scarce. Patients in this region are at risk for anemia due to endemic conditions like malaria and because transfusion services are limited.<bold>Methods: </bold>This was a prospective cohort study of ICU patients at Kamuzu Central Hospital (KCH) in Malawi. Exclusion criteria included age <5 years, pregnancy, ICU readmission, or admission for head injury. Cumulative incidence functions and Fine-Gray competing risk models were used to evaluate hemoglobin (Hgb) at ICU admission and hospital mortality.<bold>Results: </bold>Of 499 patients admitted to ICU, 359 were included. The median age was 28 years (interquartile ranges (IQRs) 20-40) and 37.5% were men. Median Hgb at ICU admission was 9.9 g/dL (IQR 7.5-11.4 g/dL; range 1.8-18.1 g/dL). There were 61 (19%) patients with Hgb < 7.0 g/dL, 59 (19%) with Hgb 7.0-8.9 g/dL, and 195 (62%) with Hgb ≥ 9.0 g/dL. Hospital mortality was 51%, 59%, and 54%, respectively. In adjusted analyses, anemia was associated with hospital mortality but was not statistically significant.<bold>Conclusions: </bold>This study provides preliminary evidence that anemia at ICU admission may be an independent predictor of hospital mortality in Malawi. Larger studies are needed to confirm this association. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00031348
- Volume :
- 87
- Issue :
- 8
- Database :
- Academic Search Index
- Journal :
- American Surgeon
- Publication Type :
- Academic Journal
- Accession number :
- 152461476
- Full Text :
- https://doi.org/10.1177/0003134820973377