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A portable digital optical kanamycin sensor developed by surface-anchored liquid crystal droplets.
- Source :
-
Journal of Hazardous Materials . Oct2021, Vol. 420, pN.PAG-N.PAG. 1p. - Publication Year :
- 2021
-
Abstract
- There is an increase in demand to develop simple, convenient, and low-cost approaches for rapid and label-free detection of antibiotics. Herein, we propose a new principle for the detection of kanamycin using the surface-anchored liquid crystal (LC) droplets. The optical images of the LC droplets uniformly change from four-clover, uniformly dark, and dark cross appearance gradually with the increase of surfactant concentration. The detection of kanamycin is fulfilled with the aid of a cationic surfactant cetyltrimethylammonium bromide (CTAB) and a kanamycin aptamer. The LC droplets show uniformly dark appearance and four-clover appearance in the presence of the aqueous solutions of CTAB and CTAB/aptamer complex, respectively. However, the specific binding of kanamycin to its aptamer can release the CTAB, which induces the uniformly dark appearance of the LC droplets. A portable device is built to measure the optical luminance of the LC droplets. This system can detect kanamycin with a concentration below 0.1 ng/mL (~0.17 nM) and also allows the detection of kanamycin in real samples such as milk and honey. Therefore, it is very promising in the development of new types of LC-based sensors by the surface-anchored LC droplets assisted with a portable optical device. [Display omitted] • The surface-anchored liquid crystal droplets are employed as the sensing platform. • The detection is based on the transition between four-clover and uniform dark appearance. • A portable optical digital device is developed to measure the luminance of the LC droplets. • The minimum detection concentration of kanamycin reaches as low as 0.1 ng/mL (~0.17 nM). • The detection of kanamycin in real samples are successfully demonstrated. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 03043894
- Volume :
- 420
- Database :
- Academic Search Index
- Journal :
- Journal of Hazardous Materials
- Publication Type :
- Academic Journal
- Accession number :
- 152554069
- Full Text :
- https://doi.org/10.1016/j.jhazmat.2021.126601