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Clinical impact of PET/MRI in oligometastatic colorectal cancer.
- Source :
-
British Journal of Cancer . Sep2021, Vol. 125 Issue 6, p975-982. 8p. - Publication Year :
- 2021
-
Abstract
- <bold>Background: </bold>Oligometastatic colorectal cancer (CRC) is potentially curable and demands individualised strategies.<bold>Methods: </bold>This single-centre retrospective study investigated if positron emission tomography (PET)/magnetic resonance imaging (MR) had a clinical impact on oligometastatic CRC relative to the standard of care imaging (SCI). Adult patients with oligometastatic CRC on SCI who also underwent PET/MR between 3/2016 and 3/2019 were included. The exclusion criterion was lack of confirmatory standard of reference, either surgical pathology, intraoperative gross confirmation or imaging follow-up. SCI consisted of contrast-enhanced (CE) computed tomography (CT) of the chest/abdomen/pelvis, abdominal/pelvic CE-MR, and/or CE whole-body PET/CT with diagnostic quality (i.e. standard radiation dose) CT. Follow-up was evaluated until 3/2020.<bold>Results: </bold>Thirty-one patients constituted the cohort, 16 (52%) male, median patient age was 53 years (interquartile range: 49-65 years). PET/MR and SCI results were divergent in 19% (95% CI 9-37%) of the cases, with PET/MR leading to management changes in all of them. The diagnostic accuracy of PET/MR was 90 ± 5%, versus 71 ± 8% for SCI. In a pairwise analysis, PET/MR outperformed SCI when compared to the reference standard (p = 0.0412).<bold>Conclusions: </bold>These findings suggest the potential usefulness of PET/MR in the management of oligometastatic CRC. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00070920
- Volume :
- 125
- Issue :
- 6
- Database :
- Academic Search Index
- Journal :
- British Journal of Cancer
- Publication Type :
- Academic Journal
- Accession number :
- 152651910
- Full Text :
- https://doi.org/10.1038/s41416-021-01494-8