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First identification and genomic characterization of equine hepacivirus subtype 2 in China.
- Source :
-
Archives of Virology . Nov2021, Vol. 166 Issue 11, p3221-3224. 4p. - Publication Year :
- 2021
-
Abstract
- Equine hepacivirus (EqHV) is a newly discovered hepatitis C virus–like virus that can infect equines. EqHV strains circulating worldwide have been classified into subtypes 1-3. In previous studies, we detected the presence of EqHV strains of subtype 1 and 3 in China. To determine whether EqHV strains of subtype 2 are prevalent in China, serum samples were collected from 133 racehorses in Guangdong province in 2021 and were tested for EqHV RNA by RT-PCR, and the positive rate was 9% (12/133). Sequencing of the NS3 gene revealed that one field strain (GD2021) had a high degree of genetic similarity to EqHV strains of subtype 2. Subsequent genome sequencing and analysis demonstrated that strain GD2021 belongs to subtype 2. The present study enriches our knowledge about the genetic diversity of EqHV in China. [ABSTRACT FROM AUTHOR]
- Subjects :
- *GENETIC variation
*NUCLEOTIDE sequencing
*SEQUENCE analysis
*RACE horses
*RNA
Subjects
Details
- Language :
- English
- ISSN :
- 03048608
- Volume :
- 166
- Issue :
- 11
- Database :
- Academic Search Index
- Journal :
- Archives of Virology
- Publication Type :
- Academic Journal
- Accession number :
- 152902259
- Full Text :
- https://doi.org/10.1007/s00705-021-05228-2