Detection of Cadmium-related ions by MALDI TOF mass spectrometry correlates with physicochemical properties of Cadmium/matrix adducts.

This work studied the relationship between the structure and the detectability of Cd-related clusters generated from Cd(OAc) 2 ·2H 2 O by matrix-assisted and matrix-free laser irradiation mass spectrometry and the compound's physicochemical properties. The limit of detection of Cd(OAc) 2 ·2H 2 O depends on the optical absorption of the matrix-analyte adducts. [Display omitted] Metal acetate complexes are highly interesting in designing and synthesizing metal–organic frameworks, which have potential applications in gas storage, molecular sieves, ion exchange, and catalysis. Cadmium is well recognized as an industrial pollutant and a food contaminant that severely affects human health. For these reasons, the detection and analysis of Cd are of great interest. A major challenge in studying cadmium compounds' structure is that Cd2+ can have a wide range of coordination numbers and diverse geometries. (MA)LDI is extremely useful for detecting Cd(OAc) 2 ·2H 2 O and investigating Cd's complex and flexible nature. We applied LDI to detect and characterize the Cd-related clusters and MALDI approach to investigate the Cd(OAc) 2 x2H 2 O reactivity and detectability with the five different organic matrices. The results revealed that in the solid-state Cd(OAc) 2 x2H 2 O tend to form coordination polymers, and in the presence of coordinating ligands (matrix molecules) form smaller complexes. In addition, the correlation between Cd-related LOD and matrix features was observed and discussed, indicating that the LODs of this analyte strongly depend on the optical absorption of the matrix-analyte adduct. [ABSTRACT FROM AUTHOR]