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Bio-inspired dynamic biomolecule assembling for fine regulation of protein activity.

Authors :
Wang, Wenxiao
Shen, Yu
Wang, Fuan
Liu, Ying
Liu, Xiaoqing
Source :
Chemical Communications. 11/4/2021, Vol. 57 Issue 85, p11205-11208. 4p.
Publication Year :
2021

Abstract

A versatile approach for the fine control of DNA-based hierarchical assembly via dual stimuli and two assembly strategies is developed. Moreover, with a reasonable design of functional thrombin aptamer structures on the formed DNA nanoassembly, it can achieve precise regulation of thrombin activity. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
13597345
Volume :
57
Issue :
85
Database :
Academic Search Index
Journal :
Chemical Communications
Publication Type :
Academic Journal
Accession number :
153242135
Full Text :
https://doi.org/10.1039/d1cc03926a