Back to Search
Start Over
One-pot synthesis of Acanthus ilicifolius Linn alkaloid 2-benzoxazolinone derivatives via a tandem Ugi 4-component coupling/haloform cyclization.
- Source :
-
Journal of Chemical Research . Sep/Oct2021, Vol. 45 Issue 9/10, p865-868. 4p. - Publication Year :
- 2021
-
Abstract
- A one-pot, base-mediated approach to Acanthus ilicifolius Linn alkaloid 2-benzoxazolinone derivatives is developed. Starting from trichloroacetic acid, o -aminophenol, substituted benzaldehydes and alkyl isocyanides, the desired 2-benzoxazolinone derivatives are obtained in good yields via a tandem Ugi condensation and intramolecular haloform cyclization at room temperature in the presence of Et3N. [ABSTRACT FROM AUTHOR]
- Subjects :
- *RING formation (Chemistry)
*ISOCYANIDES
*CONDENSATION
*COUPLES
*ALKALOIDS
Subjects
Details
- Language :
- English
- ISSN :
- 17475198
- Volume :
- 45
- Issue :
- 9/10
- Database :
- Academic Search Index
- Journal :
- Journal of Chemical Research
- Publication Type :
- Academic Journal
- Accession number :
- 153337301
- Full Text :
- https://doi.org/10.1177/17475198211024609