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Two new indole-diterpenoids from the marine-derived fungus Penicillium sp. KFD28.
- Source :
-
Journal of Asian Natural Products Research . Nov 2021, Vol. 23 Issue 11, p1030-1036. 7p. - Publication Year :
- 2021
-
Abstract
- Two new compounds named epipaxilline (1) and penerpene J (2) were isolated from the marine-derived fungus Penicillium sp. KFD28. Their structures including absolute configurations were determined on the basis of spectroscopic methods and ECD analysis. Compounds 1 and 2 showed inhibitory activities against PTP1B with IC50 values of 31.5 and 9.5 μM, respectively, and compound 2 also showed inhibitory activities against TCPTP with IC50 value of 14.7 μM. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 10286020
- Volume :
- 23
- Issue :
- 11
- Database :
- Academic Search Index
- Journal :
- Journal of Asian Natural Products Research
- Publication Type :
- Academic Journal
- Accession number :
- 153608269
- Full Text :
- https://doi.org/10.1080/10286020.2020.1849150