Component separation and large incisional hernia: predictive factors of recurrence.

Purpose: To clarify the factors related to recurrence after component separation technique (CST). Materials and methods: A retrospective study was conducted of 381 patients who underwent CST between May 2006 and May 2017 at a tertiary center. All patients had a transverse hernia defect grade W3 in EHS classification. Recurrence rate was determined by clinical examination plus confirmation by abdominal CT scan. Results: At a median of 61.6 months of postoperative follow-up, we reported 34 cases of hernia recurrence (8.9%). On multivariate analysis, BMI > 30 (OR 2.20; CI 1.10–3.91, p = 0.031), immunosuppressive drug use (OR 1.06 CI 1.48–2.75, p = 0.003) and development of surgical site infection (OR 2.7; CI 1.53–4.01, p = 0.002) were factors of recurrence after CST. There was no difference in recurrence rate among repairs of primary and recurrent hernias, urgent repair, operative time, type of prosthesis, or concomitant procedures, even planned or unplanned enterotomies. Conclusion: Obesity (BMI > 30), immunosuppressive drug use, and postoperative wound infections were predictors of recurrence after CST. [ABSTRACT FROM AUTHOR]