Osteólisis aguda secundaria a hipercalcemia de origen tumoral.

BACKGROUND: Acute hypercalcemia is a life-threatening condition that most commonly results from malignancy. Local osteolytic hypercalcemia (the local destruction of bone by tumor with calcium release) accounts for about 20% of cancer-related hypercalcemia. Destruction of bone by metastatic cancer is a late event, starting when tumor cells proliferate. Symptoms and complications of bone metastases (pain, pathologic fractures, compression of the spinal cord) become more evident as the disease becomes more extensive. CLINICAL CASE: A 27-year-old female patient that developed acute osteolysis following hypercalcemia of malignancy. CONCLUSIONS: What makes the present case unique was the rapid evolution of osteolysis during the hypercalcemic crisis, evidenced by computed tomography, in a temporality of only 14 days. [ABSTRACT FROM AUTHOR]