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Total Syntheses of Centrolobines: A Two‐Decade Journey.
- Source :
-
ChemistrySelect . 12/6/2021, Vol. 6 Issue 45, p12702-12735. 34p. - Publication Year :
- 2021
-
Abstract
- In this review we discuss the synthetic approaches of chiral and racemic forms of centrolobines from 2002 to date. The presence of unique molecular architecture of tetrahydropyran unit in centrolobine enhances its high biological activity which has created the space to the synthetic community for the last two decades to develop various routes. This review mainly emphasizes on the construction of tetrahydropyran unit and generation of chirality as a key step during the synthesis of centrolobine. Moreover, all the synthetic methods were well demonstrated and presented systematically in the chronological order. Overall this review highlights the contribution from different research groups in the total syntheses of centrolobines. [ABSTRACT FROM AUTHOR]
- Subjects :
- *RESEARCH teams
*CHIRALITY
*NATURAL products
Subjects
Details
- Language :
- English
- ISSN :
- 23656549
- Volume :
- 6
- Issue :
- 45
- Database :
- Academic Search Index
- Journal :
- ChemistrySelect
- Publication Type :
- Academic Journal
- Accession number :
- 153983986
- Full Text :
- https://doi.org/10.1002/slct.202102901