Novel Synthesis of p-t-Butylcalix[n]arenes Bearing Ethylene Glycol Ether Chains.

An approach for the synthesis of calixarene derivatives 3a–d, which contain ethylene glycol ether units at the lower rim in moderate yields, is described. The above compounds have been achieved by treating p-Butylcalix[n]arenes 1a–b(n = 6, 8) with chloroacetate 2a–b of 2-methoxyethanol and 2-(2-butoxyethoxy)ethanol in the system of K2CO3/KI/acetone. [ABSTRACT FROM AUTHOR]