Crystal structure of (+)-(1S,5S,6S,7S,10S,11S,16S)-16-hy­droxy-7-(meth­oxy­meth­oxy)-11,15,18,18-tetra­methyl-3,13-dioxo-2,4-dioxa­tetra­cyclo[12.3.1.01,5.06,11]octa­dec-14-en-10-yl benzoate.

In the fused tetra­cyclic system of the title compound, C29H36O9, the five-membered dioxolane ring adopts a twist conformation; the two adjacent C atoms deviate alternately from the mean plane of the other three atoms by −0.252 (6) and 0.340 (6) Å. The cyclo­hexane, cyclo­hexene and central cyclo­octane rings show chair, half-chair and boat-chair forms, respectively. There are three intra­molecular C—H···O inter­actions supporting the mol­ecular conformation, with one S(6) and two S(7) graph-set motifs. In the crystal, inter­molecular O—H···O hydrogen bonds connect the mol­ecules into a helical chain running along the c-axis direction, generating a C(7) graph-set motif. The chains are further linked by inter­molecular C—H···O inter­actions to construct a three-dimensional network. There is no valid C—H···π inter­action. [ABSTRACT FROM AUTHOR]