1482: IMPACT OF OBESITY ON MORTALITY IN PATIENTS WITH SEPTIC SOCK RECEIVING FIXED-DOSE VASOPRESSIN.

B Introduction: b The Surviving Sepsis Guidelines recommend initiating fixed-dose vasopressin (AVP) for patients with persistent hypotension despite norepinephrine (NE), but it is unclear if this dosing strategy is sufficient in obese patients. B Methods: b An interim analysis of a multicenter, retrospective cohort study was conducted to assess the impact of fixed-dose AVP (0.03 or 0.04 units/min) on mortality in obese patients with septic shock compared to non-obese patients. B Conclusions: b Compared to non-obese patients, obese patients with septic shock receiving fixed-dose AVP had a higher incidence of mortality. [Extracted from the article]